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Development of polymeric nanoparticles for bloodbrain barrier transferstrategies and challenges

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doi: 10.1038/nchembio.2079 68 DaiEZhangWCongDKangRWangJTangD

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Characterized Signaling Pathways Published research has identified multiple receptor-mediated signaling interactions: AMY1R / AMY2R / AMY3R (Calcitonin ReceptorRAMP Complexes) Amylin receptors are heterodimeric complexes formed by the calcitonin receptor (CTR) in association with receptor activity-modifying proteins RAMP1, RAMP2, or RAMP3, yielding AMY1R, AMY2R, and AMY3R subtypes respectively