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Description

The restoration of mTOR signaling with Fer1 rescue treatment in the context of RSL3 effects, and the genetic knockdown of GPX4, reaffirm our in vitro findings that RSL3-mediated induction of ferroptosis, mTOR pathway suppression, DNA damage and failure of DNA repair, and autophagy are GPX4-dependent processes in thyroid cancer cells

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10.3892/etm.2018.6419 Exp Therapeutic Med

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Scientific reports 12(1), 2022

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Seko Y, Sumida Y, Tanaka S, et al

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