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Netflixs limited series Big Vape: The Rise and Fall of Juul is all about the electronic cigarette startup that became a multi-billion-dollar company almost overnight, and whose success was undeniable until an epidemic caused it to go up in smoke

Of particular concern is DNA damage due to formaldehyde in the upper airways, as this damage could potentially contribute to the risk of nasopharyngeal and lung cancers specifically 3,4

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These studies show that immune cell responses are less affected by cMRTP aerosols than cigarette smoke, especially regarding their release of chemokines and cytokines such as IL-8 and TNF [76, 77]

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