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A 2025 review in Cureus walks through the physiology of why direct delivery raises peak nutrient levels you cant reach by mouth

[DOI] [PubMed] [Google Scholar] 124.Ghazvini-Boroujerdi M., Clark J., Narula N., Palmatory E., Connolly J.M., DeFelice S., Xu J., Jian B., Hazelwood S., Levy R.J

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Anti-inflammatory effect of procyanidins from wild grape (vitis amurensis) seeds in LPS-induced RAW 264.7 cells