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The reaction time was defined by placing the mouse on the hot plate, and the time was recorded when the animal showed hind paw licking or jumping, and the 45 sec period was observed to avoid tissue damage

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The majority of patients may well have suffered in silence

Analysts zeroed in on those reactions, noting that CagriSemas efficacy seemed comparable to Eli Lillys GLP-1 Zepbound, though Lillys drug did not raise the same reactions