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Redox Biol 20:4659

First, the overall gene expression patterns were visualized using principal component analysis (PCA), which revealed evident transcriptomic differences among the PBS, P-Mn@mHSA, and P-Mn/TI@mHSA groups, with no outlier samples detected (Fig

Pfizer's refocused efforts on danuglipron also ended in a decision to discontinue its development in April 2025 following a review of all available clinical trial data, regulatory input and after a single asymptomatic clinical trial participant exhibited potential drug-induced liver injury that resolved after the drug was withdrawn 25

Peptide-based in vitro assay for the detection of reactive metabolites

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