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Glutathione oxidized by allicin forms S-allylmercaptoglutathione (GSSA) Cysteine oxidized by allicin forms S-allylmercaptocysteine (CSSA) GSSA and CSSA were found to increase overall cellular glutathione levels by a measure of 15 times the amount of allicin itself, a finding that suggests that allicins reactivity with cellular thiols is one of the main drivers of its antioxidant boosting activity

Oxidative stress-induced FABP5 S-glutathionylation protects against acute lung injury by suppressing inflammation in macrophages

In vivo c-Met pathway inhibition depletes human glioma xenografts of tumor-propagating stem-like cells