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However, excessive accumulation of GSH precursors can overwhelm this reducing capacity, leading to reductive stress and aberrant mitochondrial H 2 O 2 production, a mechanism that is particularly pronounced in cancer cells characterized by elevated cysteine metabolism but limited antioxidant enzyme capacity 209

STEP 2: Focus on areas such as ankles and elbows that tend to have uneven texture

None of this is resolved either way

doi: 10.1016/j.redox.2024.103339 392 PilottoFChellapandiDMPuccioH

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