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The endothelium also generates a variety of vasodilators and vasoconstrictors, including thromboxane A 2 , NO, endothelin, and Ang II ( Endothelial dysfunction, a recognized phenomenon, exerts an influence on the permeability of the endothelial barrier, a pivotal component involved in the inflammatory response that plays a contributory role in the initiation of CVD
Insulin-like growth factor I reverses interleukin-1beta inhibition of insulin secretion, induction of nitric oxide synthase and cytokine-mediated apoptosis in rat islets of Langerhans
Ascorbic acid is a powerful antioxidant, meaning it helps protect cells from damage caused by free radicals
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