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The combination of topical and oral glutathione significantly reduced melanin index and increased skin brightness compared to placebo and monotherapy groups, with combination therapy potentially offering superior results

1 Oxidative Stress & Inflammatory Signalling Research Experimental studies suggest that GHK-Cu may reduce oxidative stress through interactions with reactive oxygen species while supporting endogenous antioxidant systems

Apigenin increased production of cleaved caspase-3, cleaved caspase-8, and cleaved PARP, which inhibited the proliferation and colony formation of HER2+ BT-474 cells (160)

Endocrinology 155 , 45914601 (2014)

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