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The prevalence of obesity and its cardiovascular complications have increased substantially in recent decades to involve younger demographics, with over 340 million children and adolescents aged 519 diagnosed as overweight or obese as of 2016 [1]

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Collectively, these findings strongly suggest that combining LPA axis inhibitors with AR-targeted therapies or chemotherapeutic agents may represent effective sensitization strategies in PCa

Cancer Cell (2008) 13:20620

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