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It binds with high affinity to HGF inducing dimerization and Met phosphorylation in the presence of subthreshold levels of HGF [Figure 2] [74]

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In addition, advanced glycocalyx fixation techniques (such as HPF and FS), along with visualization methods like TEM, reveal variations in glycocalyx thickness across vascular beds, providing new insights into its structural heterogeneity [35]

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