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Duniere, L., Frayssinet, B., Achard, C., Chevaux, E

The significance of glutathione conjugation in aflatoxin metabolism

Cellular autophagy not only plays an important role in kidney development and maintenance of homeostasis of podocytes, endothelial cells, and tubular epithelial cells but also has been implicated in the pathogenesis of several renal diseases

While several IgG Fc variants with increased plasma half-life have been developed, and some have successfully reached the clinic 23,24,25,36,53,54 , few have been Fc-engineered by a small number of amino acid substitutions that increase plasma half-life, improve biodistribution and specific effector functions, such as complement activity