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Controlled study of induced granulomas treated with NAC showed 2-fold increase in GSH, 3-fold increase in Interferon-, 2- and 3-fold reduction in tumor necrosis factor- (TNF-) at 8 and 15 days, reduced reactive oxygen ions and reduced necrosis as compared to controls (68)

Kaislasuo J, Simpson S, Petersen JF, Peng G, Aldo P, Lokkegaard E, Paidas M, Pal L, Guller S, Mor G (2020) IL-10 to TNFalpha ratios throughout early first trimester can discriminate healthy pregnancies from pregnancy losses