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The above highlights were written by Dr Lola Adekunle, PGY-2 dermatology resident at Howard University in Washington DC

So when the barrier becomes more permeable, the proposed mechanism is straightforward: substances that should stay in the gut lumen bacterial fragments, undigested food particles, pathogens cross into deeper tissue and the bloodstream, where they can drive immune activation and an increased antigenic and toxic load

It neutralizes free radicals, supports liver detoxification, recycles other antioxidants like vitamins C and E, and protects your mitochondria from oxidative damage

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Existing reviews tend to fall into two categories: overly broad analyses that emphasize reactive oxygen species (ROS) biology without sufficiently addressing GSH, or highly focused discussions on chemical linkers that overlook translational relevance