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For patients in South Florida, the heat outside the refrigerator is an especially important factor: a peptide vial left on a counter in a Doral kitchen during summer is exposed to ambient temperatures that can reach the mid-80s Fahrenheit or higher, which meaningfully accelerates degradation for any reconstituted solution left out during injection preparation

Several factors contribute to the development of hyperpigmentation, with sun exposure being the primary culprit in most cases

PMCID: PMC6770181

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