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One emerging hypothesis that may help explain this complex disease progression is the two-hit model, which proposes that DENV infection and autoantibody responses act through distinct but complementary mechanisms to drive severe disease

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Theyre signaling molecules that play a role in various physical processes

eClinicalMedicine 2026 - asymptotic regain about 75% of lost weight, roughly 60% by 52 weeks, half-life about 23 weeks

folate cycle) and adenosylcobalamin for methylmalonyl-CoA mutase (propionate metabolism)