Notably, ferritin light chain (FTL) and FTH1, which constitute ferritin (FN), and NCOA4, ATG5, and ATG7, which mediate iron-selective autophagy (i.e., ferritinophagy), were all highly expressed in the EMFF group, whereas the expression of E3 ubiquitin ligase (HERC2) ubiquitinated NCOA4 by ubiquitin-proteasome system decreased (Fig
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Additionally, fractionation of radiotherapy, which involves dividing the total radiation dose into multiple smaller doses administered over several sessions, has been shown to improve therapeutic outcomes and reduce neurotoxicity