Therefore, the purpose of this study is to discover and validate biomarkers for the diagnosis of depression in consideration of exposure to drug treatment including antidepressants that contribute to the heterogeneity of the MDD subgroup
The assessment of the levels of cysteine (Cys), homocysteine (HCys), glutamylcysteine (GluCys), glutathione (GSH) and cysteinylglycine (CysGly) was performed according to Grilo and co-authors 60 and adapted to cell culture
To date, the most promising clinical trial focuses on the progressive muscle disease mitochondrial myopathy 244
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It has been shown that hepatocyte-specific Trf knockout ( Trf -KO) mice would be more susceptible to ferroptosis in the liver under a high iron diet (HID) (Yu et al