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Extracellular GSH supplies cysteine The uptake of extracellular cystine through the cystineglutamate antiporter xCT is thought to be a major source of cysteine for tumours (Fig

Nrf2 regulates the expression of genes that are especially encoded ferritin complex constitutions (Wu et al., 2011)

Binding of AngII to its AT1 receptor leads to the activation of MAP kinases, phosphorylation of tyrosine kinases and production of ROS, all of which induce VSMC proliferation

Activation of the nrf2-ARE pathway ameliorates hyperglycemia-mediated mitochondrial dysfunction in podocytes partly through sirt1

Malvindi MA, Di Corato R, Curcio A, Melisi D, Rimoli MG, Tortiglione C, et al