Its balanced GLP-1R/GCGR receptor profile makes it a uniquely valuable research tool for laboratories studying dual incretin/glucagon pathway interactions, comparative receptor pharmacology versus single-receptor GLP-1 agonists, and the metabolic biology of simultaneous GLP-1R activation (cAMP/PKA insulin secretion pathway) and GCGR activation (hepatic glucose production, energy expenditure pathway) within a single experimental system
In the investigator-initiated trial, patients underwent two stages of randomization using the block randomization method, with random group codes generated by SAS software version 9.4
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Zhou M, Wu X, Luo J, Yang G, Lu Y, Lin S, et al
Lyophilized vials should remain dry