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Comparing the glutathione-scaffold site among a variety of other members of the thioredoxin superfamily also provides an explanation for their disulfide substrate preferences, for example, why glutaredoxins prefer GSSR in contrast to thioredoxins lacking most of the relevant residues (Fig

Obesity, cardiovascular disease, and role of vitamin C on inflammation: a review of facts and underlying mechanisms

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Contributions of the microbial hydrogen economy to colonic homeostasis

The reduced form (GSH) eliminates free radicals and, in the process, is converted into the oxidized form (GSSG)