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Hypoglycemia the primary preclinical safety signal for IGFBP-poor IGF variants

ElMekkawy HI, AlKahtani MA, Shati AA, Alshehri MA, AlDoaiss AA, Elmansi AA, Ahmed AE (2020) Black tea and curcumin synergistically mitigate the hepatotoxicity and nephropathic changes induced by chronic exposure to aflatoxinB1 in SpragueDawley rats

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Accordingly, exposure to progestin in the first 7 days of pregnancy in the animal study may be more reasonable

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