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J Allergy Clin Immunol 125(2):411418 e414 Schnyder B, Burkhart C, Schnyder-Frutig K, von Greyerz S, Naisbitt DJ, Pirmohamed M, Park BK, Pichler WJ (2000) Recognition of sulfamethoxazole and its reactive metabolites by drug-specific CD4+ T cells from allergic individuals

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In order to break this vicious cycle, insulin resistance must be taken seriously in PCOS patients

Ozaydin M, Peker O, Erdogan D, Kapan S, Turker Y, Varol E, Ozguner F, Dogan A, Ibrisim E

However, the act of doing so has a downside: it involves the continuous, insidious production of toxic molecules called free radicals or reactive oxygen species (ROS)