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Whereas porins allow molecules smaller than ~5kDa to diffuse through the outer mitochondrial membrane, the inner mitochondrial membrane is impermeable for glutathione

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10.1038/nprot.2007.199 Nat

This includes all the supplies for three 500mg injections once a week

The wealth of preclinical data suggests it holds immense promise, and it's our job to provide the highest-quality version of this tool so that researchers can continue to push the boundaries of science and potentially uncover new ways to address debilitating conditions