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Structure-Activity Relationship for Small Molecule Inhibitors of Nicotinamide N-Methyltransferase

Costello MA, Liu J, Wang Y, Qin B, Xu X, Li Q, et al

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Neither has been tested in humans, and both carry significant unknowns -- Dihexa with its retracted publication and oncological pathway concerns, PE-22-28 with its untested cognitive effects and potential seizure susceptibility