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Scientists have also identified copper as a regulator of phosphodiesterase 3 (PDE3), an enzyme involved in fat metabolism

Clinically significant vitamin B 12 deficiency and megaloblastic anemia are unlikely, unless these drug therapies are prolonged for two or more years, or if in addition, the person's dietary intake is below recommended levels

As of 2026, broad independent replication of the key BPC-157 findings in tendon and gut healing has not occurred

If nausea remains intolerable, pre-dose with 15-20g protein 30 minutes before injection to buffer the gastric effect

It is believed to promote healing in muscles, tendons, and ligaments