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(1) Dietary pattern adaptation Western populations (Europeans, Australians): the Mediterranean diet (rich in omega-3 and olive oil) reduces depression risk, as their gut microbiota (high Faecalibacterium abundance) efficiently metabolizes omega-3 into anti-inflammatory resolvins (86, 87, 331)

A 2021 meta-analysis demonstrated that individuals with asthma are at higher risk of experiencing anxiety compared to the general population [24]

The single-target competitor most people know is semaglutide (Ozempic, Wegovy), which only activates GLP-1

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582 Overactive HK2 promotes synovial cell proliferation and secretion by mediating AMPK activation of NF-B signaling