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doi: 10.1016/j.stem.2015.05.016 241 MunteanuCAchimLMuresanRSoucaMPriftiEet al

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The latter is a competitor of 2-Oxoglutarate-dependent dioxygenases such as Ten-eleven translocation methylcytosine dioxygenase and therefore induces DNA hydroxymethylation and gene upregulation 52

Nutrient interactions Biotin The chemical structure of biotin is similar to that of lipoic acid, and there is some evidence that high concentrations of lipoic acid can compete with biotin for transport across cell membranes (120, 121)