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Some of the peptide may be broken down before it can exert its full effect on systemic tissues outside the gut

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Singer P, Blaser AR, Berger MM, Calder PC, Casaer M, Hiesmayr M, et al

However, their persistence in the environment raises serious toxicological concerns, such as lung toxicity (inflammation, fibrosis, and respiratory dysfunction), skin toxicity (allergic reactions and dermatitis), liver damage (oxidative stress and lipid peroxidation), kidney toxicity (nephrotoxicity and filtration interference), and cardiovascular problems (endothelial dysfunction and arterial plaque formation)

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