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Among them, plant polysaccharides and microbial polysaccharides are more studied (Li and Zhang, 1986)

But they come with significant drawbacks: high cost, injection site reactions, increased infection risk due to immune suppression, and the development of anti-drug antibodies over time that can reduce efficacy

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c-Fos induction by gut hormones and extracellular ATP in osteoblastic-like cell lines

Weeks 5 to 8 (dose escalation to 0.6 mg) Nausea becomes more noticeable in some individuals as the dose doubles