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259 A cross-generational study has confirmed that children exposed to prenatal anticonvulsants and the mood stabilizer valproate, a well-known histone deacetylase (HDAC) inhibitor, are at increased risk of being diagnosed with autism, providing insights into the involvement of histone modifications in ASD
Furthermore, all experiments were carried out under a blind protocol, and the effects were assessed by examiners who were completely unaware of the protocol
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Block G, Jensen CD, Norkus EP, Hudes M, Crawford PB