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Some users extend to 12-week cycles, though this longer duration may increase the possibility of diminished response over time

Martin and Russell, 2007)

The mechanisms underlying weight regain are multifactorial and include metabolic adaptation with decreased energy expenditure, hormonal changes affecting appetite regulation, anatomical alterations such as gastric pouch or stoma dilation, and psychosocial factors including maladaptive eating behaviors

It prevents bacterial growth inside the vial after opening, which is why a multi-dose bacteriostatic water vial can be used for up to 28 days while standard sterile water cannot

Glutathione is an important antioxidant for gut health