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By using GHK-Cu as a single, well-characterized entity, researchers can evaluate both localized and systemic effects of copper peptide signaling without the confounding variability of mixed or poorly defined copper complexes

4.4 Treatment of goiter with Scrophulariae Radix Goiters, characterized by abnormal thyroid enlargement and symptoms such as dysphagia and dyspnea (113), arise from causes such as iodine deficiency, autoimmune disorders, thyroid nodules, and carcinoma (114)

For example, the chemotherapeutic agent doxorubicin generates ROS as part of its mechanism of action, contributing to its cytotoxic effects

[DOI] [PubMed] [Google Scholar] 113.Ntamo Y., Ziqubu K., Chellan N., Nkambule B.B., Nyambuya T.M., Mazibuko-Mbeje S.E., Gabuza K.B., Marcheggiani F., Tiano L., Dludla P.V

PMID: 22505654