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Appendix: Technical parameters For Research Use Only!

Jendiroba D, Younes A, Katz R, Hill D, Rodriguez MA, Cabanillas F, Andreeff M

Consider the overall treatment context

Routing of glucose-6-phosphate toward the pentose phosphate pathway is of bilateral importance for cancer: through the oxidative phase, the pentose phosphate pathway will yield NADPH for fatty acid synthesis, cholesterol synthesis, and the detoxification of reactive oxygen species

Heavy isotopes introduced in as L-arginine, L-ornithine, or other carbon/nitrogen donors to nitrergic metabolic pathways could in principle allow both on-target and off-target effects on nitrogen waste metabolism to be directly measured