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The device was created by Stanford graduate students as part of their thesis

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From disposable e-cigs with tobacco and menthol flavours to rechargeable starter kits with refillable cartridges, every device is available in nicotine strengths from 20mg down to nicotine-free (0mg)

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An instrument is required to be correlated with the endogenous variable but not the error term in the outcome equation (for detailed presentation of this method, see any econometric textbook, e.g., [25])