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After crunching the data, the researchers discovered that people who said they used pre-workout were significantly more likely to report that they slept an average of five or less hours a night over the past two weeks compared to those who said they didnt use pre-workout

Ahmed N, Li J, Li Y et al (2025) Symbiotic synergy: how arbuscular mycorrhizal fungi enhance nutrient uptake, stress tolerance, and soil health through molecular mechanisms and hormonal regulation

Depletion of SAMe and methionine can lead to imbalances in neurotransmitters, leading to mood disorders and cognitive dysfunction

These include chronic stress, poor diet, inadequate sleep, smoking, excessive alcohol consumption, pollution exposure, UV radiation, aging, and intense physical stress

doi: 10.1002/mco2.70168