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Owing to its high concentration in the cell (~10 3 M) 1 , the GSH/GSSG pair acts as the main intracellular redox buffer, plays a key role in the detoxification of reactive oxygen species (ROS), and participates in redox signalling 2

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Internal detox support

Briefly, 1 mg of protein was added on the IPG strip (pH 47, 24 cm), and the pre-programmed power supply (EPS 3500l, Amersham Pharmacia Biotech) was started immediately

The methionine sulfoxide reduction system: selenium utilization and methionine sulfoxide reductase enzymes and their functions