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In a related story, Business Insider reported an in-depth timeline of the success and controversies faced by JUUL.[48] According to their interview with Stanford physician Robert Jackler, JUULs product campaigns were largely youth-oriented.[49] As early as 2017, media outlets like NPR (October 2017) and USA Today (December 2017) have published news about the rising Juuling epidemic among teenagers.[50, 51] This sparked concern among school administrators and parents with the future effects of nicotine addiction

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"The tobacco epidemic: lessons from history." Journal of psychoactive drugs 21.3 (1989): 281291

Enzymes Responsible for CBD Production Via Biosynthesis Include: Cannabidiolic acid synthase Cannabichromenic acid synthase Synthetic Production of CBD Even the first FDA-approved CBD-based drug (Epidiolex) uses natural plant extracted and purified CBD