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4).8 Adolescent patients In the ALLEGRO-2b/3 trial, 15% of the population consisted of hard-to-treat adolescents with SALT 50% (severe AA), a mean disease duration of 6.5 years, and 40% with AT or AU.8 Although limited by small sample size, the results were consistent with those in the overall study population
In contrast, the M1-phenotype macrophage marker genes, including CD86 , IL-1 , inducible nitric oxide synthase (iNOS) , and tumor necrosis factor (TNF)- , were remarkably decreased in the Se@PA and SeC@PA(+) groups (Supplementary Fig
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