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daily or weekly) to correct deficiency, followed by maintenance (commonly 1 mg IM monthly or as prescribed)

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Applied within experimental research setups around regenerative mechanisms.

Therefore, the aim of this study was to evaluate the potential analgesic action of cortistatin in different established preclinical models of neuropathic pain induced by peripheral nerve injury as a consequence of chronic constriction of the nerve, partial or complete nerve transection (with or without reconstruction), or severe diabetes [23]