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Plasma lipoic acid concentrations generally peak within one hour or less and decline rapidly (6, 7, 11, 12)

The single chain pro-polypeptide is proteolytically processed by convertases to yield a mature a (heavy chain 55 KDa), and (light chain 34 KDa) heterodimer, which are bound together by a disulfide link (Stella and Comoglio, 1999

[PubMed] [Google Scholar] Carretero J, Obrador E, Anasagasti MJ, Martin JJ, Vidal-Vanaclocha F, Estrela JM