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They studied the production of cytokines in peripheral blood mononuclear cells PBMCs), and these patients (most notably those with diarrhea) showed elevated basal levels of TNF-, IL-1, and IL-6 in serum [4]

Biochem J 192 : 963966 Fagan JM, Tischler ME 1986 Reductionoxidation state and protein degradation in skeletal muscle of fasted and refed rats

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doi: 10.1038/s41556-024-01425-8