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These effects were aggravated by PRMT1 overexpression but attenuated by PRMT1 knockdown (Fig

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Clinical studies utilizing facial application of 2-3% GHK-Cu serums over 12-week periods have documented measurable improvements across multiple photoaging parameters, including 20-35% reductions in fine line depth, 15-25% improvements in skin elasticity measurements, and 25-40% increases in dermal density as assessed through high-frequency ultrasound imaging

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showed improved results in patients with metastatic CRC and led to longer survival time compared with the control group [136]