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doi:10.1093/gerona/glu057 4

Clinician-developed: Selected with guidance from Dr

5% due to alternative cytochrome P450 depending glutathione (GSH) conjugation pathway At high doses : Glucuronidation and sulfation pathways become saturated Cytochrome P450 dependent pathway becomes now more important.With depletion of hepatic glutathione, hepatotoxic, reactive, electrophilic metabolites are formed

Recombinant human insulin-like growth factor I (rhIGF I) reduces hyperglycaemia in patients with extreme insulin resistance