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Larazotide is studied as a zonulin antagonist / tight-junction regulator : in mechanistic work it is associated with promoting the reassembly of tight-junction proteins and the underlying actin cytoskeleton, blunting the gliadin- and zonulin-induced rise in permeability [4] [5]

Reported concerns include local injection reactions, potential immunogenicity from copper exposure with chronic use, and theoretical risks if peptides activate unintended growth pathways

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Dit heeft een grondiger onderzoek naar moleculaire mechanismen en door peptiden gemedieerde biologische processen mogelijk gemaakt