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These changes result in excessive intracellular iron accumulation, triggering oxidative stress and cellular damage (Ingold et al., 2018
In other embodiments, the otic gel formulations are applied via microcathethers implanted into the patient, and in yet further embodiments the formulations are administered via a pump device onto or near the round window membrane
Dendritic cells capture the allergen and present it to T-helper cells
The importance of cancer cell metabolism and the limitations of conventional cancer therapies (e.g., resistance to chemotherapy or radiotherapy) have prompted the development of strategies aimed at targeting this biological process 2
