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Nanoparticles delivering STAT3 inhibitors reduce T cell infiltration in synovial tissues (37)

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Hutton CA, Southwood TJ, Turner JJ

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Furthermore, when apoptosis and necroptosis fail to occur, caspase-8 can be involved in the activation of caspase-1 and inflammasome to trigger pyroptosis, a strongly proinflammatory cell death modality associated with the release of IL-1 and IL-18 [145, 146]