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Although Compounds 1.62 and 1.64 lost activity for the GPx and/or GR enzymes responsible for the antioxidative effect and regeneration of the thiol group of GSH using other reductant sources, respectively, these compounds were still able to rescue the cell death of UVA irradiated cells as the neutralisation the free radicals produced by UVA irradiation could be achieved by other pathways

3A-3Eshow cytocochleograms of percent missing cells (y-axis) of inner hair cells (IHC) and outer hair cells (OHC) following 9 mg/kg (FIG

in total, 9 genera (including the unclassified group) and 38 metabolites met these criteria (metabolites published in Sampson et al., 2021 13 )

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[DOI] [PubMed] [Google Scholar] 105.Issels R.D., Nagele A., Eckert K.G., Wilmanns W