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To test whether -KG insufficiency results in NADPH depletion, we used genetically encoded fluorescent sensors to monitor cytosolic (iNap1) and mitochondrial (iNap3) NADPH levels, as described previously 29

Peak plasma concentration will occur overnight, but the initial receptor priming happens during the post-training window when GLUT4 is still elevated

Fixed cells were stored at 20 C

For the five samples, a high correlation was found between the 16S rRNA gene amplicon-based SFB relative abundance and coverage of the Human-SFB-SE genome by WGS read mapping (R-squared = 0.9754, p -value = 0.0016) (Fig

Additionally, glutathione supplements have been shown to reduce inflammation and oxidative stress in the liver, further supporting its health